The results of the study will be used to enable the NHS Breast Screening Programme decide whether and how to implement tomosynthesis for routine screening
Primary objectives.
To compare the
Secondary objectives.
- To demonstrate non-inferiority of DBT + S2D compared to DBT + 2DDM.
- To measure the impact of DBT + 2DDM screening on screening recall rates, benign biopsy rates at diagnostic assessment and at surgery.
- To measure the effect of DBT + 2DDM screening compared to 2DDM in patient groups according to breast density, type of screen, age.
- To develop methods for measuring reader performance with DBT + 2DDM screening.
- To carry out retrospective reader studies to measure the effect of
other screening strategies – 2DDM vs DBT alone, 2DDM vs DBT + synthetic 2D, 2DDM vs 2DDM + limitedtomo views. - To compare patient preferences for breast cancer screening with 2DDM + DBT vs 2DDM.
- To develop & evaluate Artificial Intelligence Algorithms for the Analysis of DBT images