{"id":202,"date":"2025-04-10T14:08:28","date_gmt":"2025-04-10T14:08:28","guid":{"rendered":"http:\/\/10.161.128.46\/zkhan\/nccpm\/?page_id=202"},"modified":"2025-08-05T10:23:29","modified_gmt":"2025-08-05T10:23:29","slug":"cascade","status":"publish","type":"page","link":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/research-projects-completed\/cascade\/","title":{"rendered":"CASCADE"},"content":{"rendered":"<div style=\"margin-left: 40px; margin-right: 20px\">\n\n\n<h5 class=\"wp-block-heading\"><\/h5>\n\n\n\n<p><strong>Risk-based breast cancer screening: Is there a role for breast density?<\/strong><br>&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Research Objectives:<\/strong><\/td><td>This case-control study investigated the effect of breast composition on risk of screen-detected and interval cancers, by time since last screen and by lymph node status. The primary objective was to look at the effect of breast composition on risk of screen-detected and interval cancers, by time since last screen. A secondary objective, was to look at the effect of breast composition measures on risk of recall and risk of &#8216;potentially missed&#8217; cancers, interval cancers for which a lesion can be indentified retrospectively on the previous mammogram.<\/td><\/tr><tr><td><strong>Start date:<\/strong><\/td><td>1st January 2017<\/td><\/tr><tr><td><strong>Duration:<\/strong><\/td><td>12 months<\/td><\/tr><tr><td><strong>Status:<\/strong><\/td><td>Completed<\/td><\/tr><tr><td><strong>Funding:<\/strong><\/td><td>The project was led by Prof. Stephen Duffy at the Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London with funding of \u00a3110k from the American Cancer Society.<\/td><\/tr><tr><td><strong>NCCPM role:<\/strong><\/td><td>Staff at NCCPM assembled a dataset comprising mammograms from the OPTIMAM Image database for 302 screen-detected cancers, 297 interval cancers and 605 normal controls. Volpara software was used at NCCPM to determine density for each mammogram.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n<\/div\n<br>\n<br>\n<br>","protected":false},"excerpt":{"rendered":"<p>Risk-based breast cancer screening: Is there a role for breast density?&nbsp; Research Objectives: This case-control study investigated the effect of breast composition on risk of screen-detected and interval cancers, by time since last screen and by lymph node status. The primary objective was to look at the effect of breast composition on risk of screen-detected [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":198,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"home-page.php","meta":{"_acf_changed":false,"saved_in_kubio":true,"footnotes":""},"class_list":["post-202","page","type-page","status-publish","hentry"],"acf":[],"kubio_ai_page_context":{"short_desc":"","purpose":"general"},"_links":{"self":[{"href":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/wp-json\/wp\/v2\/pages\/202","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/wp-json\/wp\/v2\/comments?post=202"}],"version-history":[{"count":6,"href":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/wp-json\/wp\/v2\/pages\/202\/revisions"}],"predecessor-version":[{"id":2122,"href":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/wp-json\/wp\/v2\/pages\/202\/revisions\/2122"}],"up":[{"embeddable":true,"href":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/wp-json\/wp\/v2\/pages\/198"}],"wp:attachment":[{"href":"https:\/\/medphys.royalsurrey.nhs.uk\/nccpm\/wp-json\/wp\/v2\/media?parent=202"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}